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KMID : 0032220210330030271
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Annals of Dermatology
2021 Volume.33 No. 3 p.271 ~ p.274
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A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
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Kim Min-Su
Lee Ji-Yun
Kim Soo-Chan
Na Jung-Im
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Abstract
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Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the diagnosis and treatment of the underlying malignancy. However, involvement of the respiratory system is typically unresponsive to treatment. Herein, we report the case of a 44-year-old female diagnosed with paraneoplastic pemphigus with underlying follicular lymphoma treated with a chemotherapy regimen including rituximab. Her skin lesions and underlying lymphoma responded to treatment, but bronchiolitis obliterans continued to progress and resulted in fatal respiratory failure.
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KEYWORD
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Bronchiolitis obliterans, Follicular lymphoma, Paraneoplastic pemphigus, Rituximab
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